JBRF investigators are currently conducting studies in the fields of phenomenology (diagnosis), neuroimaging, neuropsychological testing, and molecular genetics. Through our web site and the screening instruments JBRF researchers have developed, we have been able to collect information on thousands of children with bipolar disorder. This is the largest data base of children with bipolar disorder in the world. The large amount of data collected has allowed us to develop a fine-grained view of the illness. This view of the clinical condition informs all of our research studies.
Below are papers describing our research and findings that have been recently published in peer-reviewed journals.
Journal of Psychiatry and Brain Science:
- Thermoregulatory Fear of Harm Mood Disorder: In Depth Exploration of a Unique Juvenile-Onset Phenotype That Provides a Parsimonious Clinical Description of Certain Youths with Highly Comorbid Treatment Refractory Psychiatric Disorders
Current Opinion in Pediatrics:
Journal of Clinical Medicine:
- Alterations in Skin Temperature and Sleep in the Fear of Harm Phenotype of Pediatric Bipolar Disorder
Journal of Clinical and Experimental Neuropsychology:
- Neuropsychological factors differentiating treated children with pediatric bipolar disorder from those with attention-deficit:hyperactivity disorder
- Clinical experience using intranasal ketamine in the longitudinal treatment
of juvenile bipolar disorder with fear of harm phenotype
- Clinical experience using intranasal ketamine in the treatment of pediatric bipolar disorder/fear of harm phenotype
- A strategy for identifying phenotypic subtypes- Concordance of symptom dimensions between sibling pairs who met screening criteria for a genetic linkage study of childhood-onset bipolar disorder using the Child Bipolar Questionnaire
- Factors associated with parent-reported suicide threats by children and adolescents with community-diagnosed bipolar disorder