Thermoregulatory Fear of Harm Mood Disorder* is a legitimate psychiatric disorder with a known effective treatment.

Learn About This Groundbreaking New Diagnosis, How To Recognize It, And How To Treat It.

Help your patients and be a part of ushering in a new era in mental healthcare.

  • JBRF researchers have identified a biological marker for Fear of Harm
  • This is the first biomarker ever associated with a mental illness
  • Thermodysregulation results in both somatic and behavioral symptoms
  • Medications that treat the biological dysfunction resolves these symptoms

* Fear of Harm

Fear of Harm Diagnostic Criteria

  • 1) Episodic and Abrupt Transitions in Mood States
  • 2) Fear of Harm
  • 3) Thermoregulatory Disturbance
  • 4) Aggression
  • 5) Sleep/Wake Disturbances
  • 6) Symptoms Are Not Due to a General Medical Condition
  • 7) A Family History of Recurrent Mood Disorder or Alcoholism


  • JBRF has acquired the world’s largest data set of symptoms experienced by children at risk for, or diagnosed with bipolar disorder.
  • From this, investigators have defined a syndrome called Fear of Harm (FOH), a severe and often treatment-resistant illness.
  • 1/3 of the children and adults diagnosed with bipolar disorder likely have Fear of Harm.
  • Investigators have been able to describe a neuroanatomical model of the illness and have determined that problems with body temperature regulation underlie the condition.
  • Studies are underway to explore the observed effectiveness of ketamine to reduce the symptoms of FOH.


The Fear of Harm Training Courses for practitioners are custom designed programs for clinicians and prescribers. The courses teach how to recognize, diagnose, and treat Fear of Harm whether you are a therapist, psychologist, social worker, or teacher, or if you are a medical professional, APN, or psychiatrist. These courses will support you as you help children and families get their lives back.

The Professionals Training Program

  • Access the most up to date information uncovered by JBRF researchers as they learn more about Fear of Harm in clinical research studies.
  • Join supervision sessions led by a trained professional as you learn how to successfully diagnose and effectively treat Fear of Harm.
  • Develop the competency to add treatment of Fear of Harm to the menu of services you offer to your clients and patients.

To become a part of this program please contact us.

Testing for Bipolar Disorder and Fear of Harm

Clinician's Pathway Program

This diagnostic assessment program for juvenile bipolar disorder is designed for use in clinical and research settings to screen for bipolar disorder in children from parent and child reports.
Get Started:
*Illustrated by Karl Gude, director of graphic design at Newsweek magazine

Utilize in your practice a diagnostic tool that is 96% accurate in diagnosing bipolar disorder and Fear of Harm.

Developed by JBRF Research Director, Demitri Papolos, MD, the CBQ and the J/J are the only diagnostic tools designed specifically for children with bipolar disorder.