The Difference a Diagnosis Makes: How Understanding Fear of Harm Syndrome May Help Save Your Child

Alice* is artistic, intelligent and on her third
school placement. Her parents remember that she was always very hot as a baby. Growing up she would constantly kick off the bed covers, often waking up in a pool of sweat with terrifying nightmares that no one could explain. She was often afraid to go to sleep. She would worry about everything, howled when she was separated from her parents and often demanded to sleep in their bed.

Q&A on the significance of the longitudinal study of intranasal ketamine in a novel phenotype of bipolar disorder

Clinical experience using intranasal ketamine in the longitudinal treatment of juvenile bipolar disorder with fear of harm phenotype. Papolos D1, Frei M2, Rossignol D3, Mattis S4, Hernandez-Garcia LC5, Teicher MH5.J Affect Disord. 2017 Aug 30. 1. Were you surprised by your findings, why, why not? I was surprised by the magnitude of the effect when…

To Our Friends & Supporters

Many thanks for your continuing support of the Juvenile Bipolar Research Foundation. All progress we make is attributable to your extraordinarily consistent generosity.

Your contributions have helped fund research that has resulted in ground‐breaking studies that identified a novel subtype, and an effective treatment for the most severe form of juvenile‐onset bipolar disorder (referred to as the Fear of Harm subtype). The research led to a major expansion of knowledge in the field.

Recruiting for Treatment Study – video

This is a video that documents the experiences of three children who have participated in the pilot study of intranasal ketamine as a treatment for juvenile bipolar disorder. Dr. Demitri Papolos, Director of Research for JBRF, developed and implemented a pilot study to explore the efficacy of intranasal ketamine as a treatment for children who…