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This is a video that documents the experiences of three children who have participated in the pilot study of intranasal ketamine as a treatment for juvenile bipolar disorder.

Dr. Demitri Papolos, Director of Research for JBRF, developed and implemented a pilot study to explore the efficacy of intranasal ketamine as a treatment for children who have been diagnosed with early-onset bipolar disorder.  The study is in its fourth year and includes over 20 children and teens who fit the Fear of Harm profile (click here for a description of the Fear of Harm Phenotype) and struggle with thermoregulatory dysfunction (click here to access the study relevant to thermoregulation).

The children and teens participating in this pilot study had symptoms that were resistant to traditional treatment protocols for bipolar disorder.

Please click here to view the video.