Q&A on the significance of the longitudinal study of intranasal ketamine in a novel phenotype of bipolar disorder

Clinical experience using intranasal ketamine in the longitudinal treatment of juvenile bipolar disorder with fear of harm phenotype. Papolos D1, Frei M2, Rossignol D3, Mattis S4, Hernandez-Garcia LC5, Teicher MH5.J Affect Disord. 2017 Aug 30. 1. Were you surprised by your findings, why, why not? I was surprised by the magnitude of the effect when…

To Our Friends & Supporters

Many thanks for your continuing support of the Juvenile Bipolar Research Foundation. All progress we make is attributable to your extraordinarily consistent generosity.

Your contributions have helped fund research that has resulted in ground‐breaking studies that identified a novel subtype, and an effective treatment for the most severe form of juvenile‐onset bipolar disorder (referred to as the Fear of Harm subtype). The research led to a major expansion of knowledge in the field.

Recruiting for Treatment Study – video

This is a video that documents the experiences of three children who have participated in the pilot study of intranasal ketamine as a treatment for juvenile bipolar disorder. Dr. Demitri Papolos, Director of Research for JBRF, developed and implemented a pilot study to explore the efficacy of intranasal ketamine as a treatment for children who…

JBRF Genetic Study

The Goal The goal of the Genetics Study is to better understand the genetic basis of juvenile bipolar disorder.  Greater comprehension of the biological basis of the disorder will lead to better methods of prevention and treatment. Genetics 101 The human body is composed of trillions of cells.  Each one of these cells contains chromosomes.…